NYBORGLAB ONLINE

Holli Giebler

Research Associate IV
E-mail | Holli.Giebler@ColoState.edu

Research Focus

• Advice and technical support
• Lab psychologist
• Lab mom

Nyborg Lab Publications

• Kim, Y.-M., Ramírez, J.A., Mick, J.E., Giebler, H.A., Yan, J.-P. and Nyborg, J.K. Molecular Characterization of the Tax-containing HTLV-1 Enhancer Complex Reveals a Prominent Role for CREB Phosphorylation in Tax Transactivation. J. Biol. Chem. 282, 18750-18757 (2007).

• Georges, S.A. , Giebler, H.A., Cole, P.A., Luger, K., Laybourn, P.J., and Nyborg, J.K. Tax Recruitment of CBP/p300, via the KIX Domain, Reveals a Potent Requirement for Acetyltransferase Activity that is Chromatin-Dependent and Histone Tail-Independent. Mol. Cell. Biol. 23, 3392-3404 (2003).

• Giebler, H.A., Lemasson, I. and Nyborg, J.K. p53 recruitment of CBP mediated through phosphorylated CREB: A novel pathway for tumor suppressor regulation. Mol. Cell. Biol. 20: 4849-4858 (2000).

• Van Orden, K., Giebler, H.A., Lemasson, I. , Gonzales, M. and Nyborg, J.K. Binding of p53 to the KIX domain of CBP: A potential link to HTLV-I associated leukemogenesis. J. Biol. Chem. 274, 26321-26328 (1999).

• Yan, J.-P., Garrus, J.E., Giebler, H.A., Stargell, L.A. and Nyborg, J.K. Molecular Interactions Between the Human T-Cell Leukemia Virus Tax Protein and the Cellular Coactivator CBP. J. Mol. Biol. 281: 395-400 (1998).

• Lenzmeier, B.A., Giebler, H.A. and Nyborg, J.K. HTLV-I Tax Requires Direct Access to DNA for Recruitment of CBP. Mol. Cell. Biol. 18:721-731 (1998).

• Giebler, H.A., Loring, J., Van Orden, K., Colgin, M., Garrus, J., Escudero, K., Brauwieler, A. and Nyborg, J.K. Anchoring of CBP to the HTLV-I Promoter: A Molecular mechanism of Tax Transactivation. Mol. Cell. Biol. 17: 5156-5164 (1997).

• Uittenbogaard, M.N., Giebler, H.A., Reisman, D. and Nyborg, J.K. Transcriptional Repression of p53 by the Human T-Cell Leukemia Virus type I Tax Protein, J. Biol. Chem. 270: 28503-28506 (1995).

• Brauweiler, A., Garl, P., Franklin , A.A., Giebler, H.A. and Nyborg, J.K. A Molecular Mechanism for HTLV-I Latency and Tax Transactivation. J. Biol. Chem. 270: 12814-12822 (1995).

• Baranger, A.M., Palmer, C.R., Hamm , M.K., Giebler, H.A., Brauweiler, A., Nyborg, J.K. and Schepartz, A. Mechanism of DNA Binding Enhancement by the HTLV-I Transactivator Tax. Nature 376: 606-608 (1995).